This guidance is based on a global literature review, analyses of national policies, and a novel approach to rapidly crowdsource further published and unpublished evidence about AEPs. One hundred and thirty-six relevant sources were identified, 76% of which are grey literature. Of those explored, eight countries in Sub‑Saharan Africa were selected for deeper exploration: Ethiopia, Ghana, Kenya, Liberia, Nigeria, Sierra Leone, South Sudan, and Uganda. This paper is intended to share lessons learned from each of these countries’ journeys, and not to promote AEPs or review the technical programming aspects of AEPs. Its lessons can be applied globally, and the data and research needs identified can help prioritise funding and research.